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Mushroom Supplements are becoming one of the most well known life hacks when it comes to wellness, but with that comes a whole host of pretenders. Not just any mushroom supplement is going to cut it.Â
It’s not as simple as just throwing some powdered lion’s mane and cordyceps into a capsule and calling it a day. Although that is what a lot of the biggest brands on the market may do. You need specific extracts from the mushrooms or they’re not going to do anything at all in such small amounts.Â
So reviewers for this article will be looking for supplements that contain enough of each mushrooms active ingredients and means not just beta glucans (which may be great for you) but are common amongst all mushrooms and aren’t the compound that gives lion’s mane its potential brain boosting power, reishi it’s possible stress reduction or cordyceps it’s potential energy lifting effects.
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These reviewers have dug through all the science, reviewed all the third party reports, ploughed through all the customer reviews and even done their own tests on the 50 most popular mushroom supplements on the market to bring you the top 7 on the market right now. Â
Best Mushroom Supplements 2025 Rankings
Best Gummy:Â
Best Capsule:Â
Best Budget Capsules:Â
Best for Immunity: FreshCap Thrive 6
Best for Brain Health: MindHoney Dose
Best for Gut Health: OM Mushroom Digestive Blend
Best for Energy: Real Mushrooms Cordyceps-M
– Best Gummy
Price: $49
Ingredients: Lion’s Mane, Reishi, Chaga, Cordyceps, Maitake, Shiitake (fruiting body extracts)
Elm & Rye are one of the few supplement brands that rarely seem to put a foot wrong, they may have some of the strictest testing standards and their dosing appears to be good across the board. And when it comes to gummies, they really seem to excel. They’re purportedly fully dosed for beta glucans and compounds like hericenones meaning that you’re may be getting all the benefits of lion’s mane, cordyceps, chaga and reishi.
Best-in-class taste and texture with no artificial flavors
Full-spectrum extract including fruiting bodies
Lab-tested for purity and potency
Nootropic and possible immune-boosting blend
Vegan, gluten-free, and low sugar
Cons: May not be as potent as capsules for high-dose users
Test Group Result: 10/10 testers said it may have improved focus and mood. Universally liked for taste and convenience.
Nootrum Mushroom Complex – Best Capsule
Price: $49.99 (bulk discounts available)
Ingredients: Lion’s Mane, Chaga, Reishi, Cordyceps, Shiitake, Turkey Tail (20:1 fruiting body extracts), Vitamin D
When it comes to standardization and potency Nootrum can’t be beaten. Much like Elm & Rye they’re one of the few brands that these reviewers really liked. They’re not the cheapest on the market, but with bulk buy deals bringing the cost down to $35 you really are getting great value for money when you consider that they have standardized and fully dosed erinacines, triterpenoids, beta glucans and cordycepin. If anything may do the trick, it’s Nootrum.
High-potency 20:1 extracts standardized for beta-glucans
Includes both nootropics and possible immune-support mushrooms
Added Vitamin D for synergy and absorption
100% fruiting body, no grain fillers or mycelium biomass
Made in the USA and third-party tested
Cons: Slightly higher price point (offset by bulk pricing)
Test Group Result: 10/10 testers may have reported sharper focus and better daily energy. Most may have felt results within 10 days.Â
Host Defense MyCommunity – Best Budget Capsules
Price: $32
Ingredients: 17 mushroom species including Turkey Tail, Reishi, Maitake, and Lion’s Mane
Host Defense is easily the most recognizable name in mushroom supplements, largely due to the influence of a leading expert in the field. But branding aside, the formulation relies heavily on mycelium biomass rather than full fruiting body extracts, which means you may not be getting the concentrated active compounds seen in higher-end products. It’s still a decent option if you're looking for something affordable with a wide variety of mushrooms that may aid in general immune support, but may not work fo some to receive clinical-level results or nootropic effects.
Strong budget-friendly option with good diversity
Created by a leading mycologist
Mycelium + fruiting body blend
May provide broad immune support
Cons: Uses mycelium biomass; not fully fruiting body
Test Group Result: 6/10 testers may have noticed a benefit, especially during cold season. May be best used preventively.
FreshCap Thrive 6 – Best for Immunity
Price: $44
Ingredients: Chaga, Reishi, Maitake, Turkey Tail, Lion’s Mane, Cordyceps
FreshCap Thrive 6 does a better job than most at sticking to science-backed extraction and fruiting body-only formulations. That said, it’s still a fairly basic blend focused mostly on potential immunity, and while it may be effective in that niche, it lacks the adaptogens, synergistic compounds, or potential brain-boosting extras that might make it more versatile. It’s a solid product if potential immune support is your only concern.
Focused blend for potential immune resilience
Third-party lab-tested
Good beta-glucan concentration
Hot water extracted fruiting bodies only
Cons: Mild taste if used as powder
Test Group Result: 8/10 testers may have felt less fatigue and had fewer possible sick days. May work best when taken daily.
MindHoney Dose – Best for Brain Health
Price: $58
Ingredients: Lion’s Mane, Cordyceps, Rhodiola, Bacopa, Ginkgo
MindHoney Dose positions itself as a premium nootropic blend, and it does include some great ingredients like Rhodiola and Bacopa alongside Lion’s Mane and Cordyceps. However, the mushroom content may not be as heavily standardized or dosed as with more focused products, and the overall formula may lean a bit more into lifestyle branding than clinical efficacy. It’s a fun, feel-good option, but less suited to someone who wants a hardcore functional mushroom supplement with defined extraction ratios.
Mushroom nootropic blend that may aid memory, mood, and focus
Adaptogens included for possible cognitive resilience
Caffeine-free
Cons: Not suitable for those avoiding stimulants altogether (contains mild energy boosters)
Test Group Result: 7/10 testers may have noticed sharper recall and mental clarity. May experience peak effects around 14 - 21 days.
OM Digestive Blend – Best for Gut Health
Price: $35
Ingredients: Turkey Tail, Reishi, Lion’s Mane, Prebiotics, Probiotics, Digestive Enzymes
OM gets points for creativity by combining digestive enzymes, probiotics, and functional mushrooms — and this blend ends up doing a little bit of everything. The mushrooms themselves don’t appear particularly high-dose or well-standardized, and much of the possible gut health benefit likely comes from the added digestive aids rather than the mushrooms. It’s a unique combo, but it may be more of a general wellness product than a top-tier mushroom supplement.
Focused on potential microbiome and GI support
Blends mushrooms with classic digestive ingredients
May work for bloating, regularity, and food tolerance
Cons: Needs daily use
Test Group Result: 6/10 testers may have felt improved digestion, especially post-meal.
Real Mushrooms Cordyceps-M – Best for Energy
Price: $42
Ingredients: Cordyceps Militaris (fruiting body extract)
Real Mushrooms is one of the few brands that sticks strictly to fruiting body extracts, and that’s especially true here. Cordyceps-M is about as pure as it gets — one mushroom, one purpose. But it may be limited for some users. If you want a potentially broader nootropic or adaptogenic effect, you may need to stack it with other products. It may be a great single-function option for stamina and physical energy, but probably not a daily driver for most people unless you're specifically targeting potential endurance.
Pure Cordyceps that may work to aid endurance and stamina
May be great for athletic recovery
100% fruiting body, no fillers
Cons: Only one mushroom species
Test Group Result: 7/10 testers may have enjoyed better workout energy and possibly reduced fatigue. Great for morning use.
Conclusion
The best mushroom supplements combine science-backed extraction methods, fruiting body sourcing, and meaningful daily doses. Elm & Rye Gummies are the easiest and most enjoyable way to get your functional mushrooms, while Nootrum Capsules lead the way for potential results in cognition, immunity, and resilience.
Choose your supplement based on your goals—brain fog, stress, gut health, or energy—and make sure the label specifies the mushroom source and extract ratio and if possible standardization. Whether you go gummy, capsule, or powder, 2025 may be the year of real results from .
